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TRIKAFTA is a breakthrough treatment for people with CF age 12
years and older with at least one copy of the F508del mutation or
at least one other responsive mutation.

CF will always be part of the equation, but you know there's more
to who you are.

Make TRIKAFTA part of your equation—a triple combination
therapy that treats the underlying cause.

$25 copay (PCP) $30 copay (SPC) $50 copay (observation room) $15 copay (PCP) $25 copay (SPC) Urgent care: $25 copay: $20 copay: Emergency: $50 copay: $50 copay: Prescription drug coverage: Tier 1 $0 copay select generic drugs $15 copay (30-day retail) $37.50 copay (90-day mail-order) Tier 2 $45 copay (30-day retail) $112.50 copay (90-day mail. $20 copay PCP/ $70 copay SPC; deductible does not apply and 25% coinsurance for other outpatient services Not Covered None Habilitation services $20 copay PCP/ $70 copay SPC; deductible does not apply and 25% coinsurance for other outpatient services Not Covered Skilled nursing care 25% coinsurance Not Covered. Copay/visit (PCP) $45 copay/visit (SPC) $10 copay/groupvisit Not Covered -None- Inpatient services coinsurance After Deductible Not Covered Preauthorization is required. If you are pregnant Office visits No Charge After Initial Visit $35 copay/visit (PCP) $45 copay/visit (SPC) Not Covered Cost sharing does not apply to certain.

TRIKAFTA is a breakthrough
treatment for people with CF age
12 years and older with at least
one copy of the F508del mutation
or at least one other responsive mutation.

CF will always be part of the equation,
but you know there's more
to who you are.

Make TRIKAFTA part of your equation—a triple combination
therapy that treats the underlying cause.

F508del/F508del

People with CF pictured may or may not be taking TRIKAFTA.

Based on the information entered, you may be eligible for TRIKAFTA.

Talk with your healthcare provider to see if TRIKAFTA is right for you.

Here is some information about TRIKAFTA that may be helpful:

Neither CF gene mutation you entered is eligible for TRIKAFTA.

News software for mac. Talk with your healthcare provider to discuss your CF care plan and treatment options that may be right for you.

You can view the list of eligible mutations here.

Get answers to common questions, such as:

  • How does TRIKAFTA work?

  • What are the study details and results?

  • What are the possible side effects?

Get to Know Vertex GPS™:!break Guidance & Patient Support

Vertex GPS offers eligible patients ongoing one-on-one support, right from the start of treatment. Patient Support Specialists can help you navigate questions about insurance, reimbursement, and potential co-pay assistance. You can even get tips for your Vertex treatment and resources that may help you stay on track. No matter where you’re headed, Vertex GPS is with you along the way.

Spc copay
Divigel® (estradiol gel) 0.1% is indicated for the treatment of moderate to severe hot flashes due to menopause.

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT DIVIGEL (AN ESTROGEN HORMONE)?

  • Using estrogen-alone increases your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using Divigel. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual bleeding to find out the cause.
  • Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline of brain function)
  • Using estrogen-alone may increase your chances of getting strokes or blood clots
  • Using estrogen-alone may increase your chance of getting dementia, based on a study of women 65 years of age or older
  • Do not use estrogens with progestins to prevent heart disease, heart attacks, strokes or dementia
  • Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots
  • Using estrogens with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older
  • Only one estrogen-alone product and dose has been shown to increase your chances of getting strokes, blood clots, and dementia. Only one estrogen with progestin product and dose has been shown to increase your chances of getting heart attacks, strokes, breast cancer, blood clots, and dementia.
    Because other products and doses have not been studied in the same way, it is not known how the use of Divigel will affect your chances of these conditions. You and your healthcare provider should talk regularly about whether you still need treatment with Divigel.

Do not use Divigel if you have unusual vaginal bleeding, currently have or have had certain cancers, including cancer of the breast or uterus (womb), had a stroke or heart attack; currently have or have had blood clots, currently have or have had liver problems, have been diagnosed with a bleeding disorder, or if you are allergic to Divigel or any of its ingredients.

Tell your healthcare provider about all of your medical problems and the medicines you take, if you are going to have surgery or will be on bed rest, and if you are breastfeeding.

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Call your healthcare provider right away if you get any of the following symptoms: new breast lumps, unusual vaginal bleeding, changes in vision or speech, sudden new severe headaches, or severe pains in your chest or legs with or without shortness of breath, weakness and fatigue.

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The most common side effects of Divigel include irregular vaginal bleeding or spotting; breast tenderness, vaginal yeast infection, cold, and upper respiratory tract (nose, sinuses, pharynx or larynx) infection.

Serious but less common side effects include stroke, blood clots, heart attack, cancer of the lining of the uterus (womb), breast cancer, cancer of the ovary, dementia, gallbladder disease, high blood calcium (hypercalcemia), high blood pressure, high triglyceride (fat levels in your blood), liver problems, low thyroid levels in your blood, fluid retention, low blood calcium (hypocalcemia), enlargement of benign uterus tumors (“fibroids”), worsening of angioedema (swelling of face and tongue), changes in certain laboratory test results, and high blood sugar.

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Alcohol-based gels are flammable. Avoid fire, flame or smoking until the gel has dried.

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You may report side effects to Vertical Pharmaceuticals, LLC at 1-877-482-37881-877-482-3788, or to the FDA at 1-800-FDA-10881-800-FDA-1088.

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For more information, please see full Patient Information for Divigel and talk to your healthcare provider. You may also call customer service at 866-600-4799866-600-4799 or visit www.divigel.com.